Freshman Athena Gee’s third 3-pointer of the night, with 2:15 remaining, lifted the Panthers (8-1) over the visiting Falcons (3-8).
The Falcons had erased a nine-point deficit and went ahead 37-35 on two free throws from Isabelle Orlando, but the Panthers tied it on a jumper from Angel Huntsman, then Huntsman set up Gee for the winner.
Orlando missed a potential tying 3 just before the buzzer.
Freeport was paced by 16 points and 16 rebounds from Mason Baker-Schlendering.
Madilyn Onorato led NYA with 12 points. Gee had nine, Graca Bila eight and Huntsman seven.